Engineering Minute

Engineering Minute – Integrating Implantable Medical Devices

New Way to Integrate Implantable Medical Devices

When working with implantable medical devices, the key is a device that seamlessly integrates with the host tissues. In order to achieve this, there needs to be robust attachment of biological molecules to the devices surface. While proteins have successfully been used in the past, they don't always survive the sterilization process. Now, a team of researchers at University of Sydney have uncovered a way to better integrate implantable devices into host tissue, improving success rates and decreasing infection and rejection. Using applied electric fields and buffer chemistry, the team discovered several new mechanisms to control peptide attachment. They focus on tuning the orientation of extremely small biomolecules that are resilient during sterilization and can be produced synthetically. The team hopes to have this technology available to patients within 5 years. Read more about their efforts at the University of Sydney