Dr. Ottavio Alfieri's paper on Novel Suture Device For Beating-Heart Mitral Leaflet Approximation, details the successful use of Synectic developed mitral valve suture device in mitral valve repair on a beating heart without cardiopulmonary bypass. Read more about the study at The Annals of Thoracic Surgery.

The experimental device. (A) The suture device on the top, the knot pusher on the bottom, and the monofilament sutures with straight needles in the middle. The device passes into the cardiac chambers through a port access cannula in the left atrium (pictured in Fig 2). (B) Close-up view of the distal end of the suture device showing the two suction parts and the four needles partially deployed. (C) Schematic depiction of the method of firing of the stitches through the mitral valve (MV) leaflets. (LA = left atrium; LV = left ventricle.)